Molecular Formula | C22H27Cl3N2OS |
Molar Mass | 473.88658 |
Melting Point | 250-260° (dec) |
Solubility | Very soluble in water; sparingly soluble in ethanol (96%); very slightly soluble in ether . |
Storage Condition | Sealed in dry,Room Temperature |
Toxicity | LD50 in male mice (mg/kg): 111 i.v. (Lassen) |
Nature:
Dichlorothiazide hydrochloride is a white solid that is soluble in water and ethanol.
Method:
The synthesis method of dichlorothiol dihydrochloride is relatively complex and usually involves multi-step reactions. One possible synthesis route is to first synthesize thiol esters, then undergo chlorination reactions, followed by catalytic amidation reactions, and finally react with dihydrochloride to obtain dichlorothiol dihydrochloride.
Security:
1. During use, there may be some side effects such as headache, fatigue, fainting, etc.
2. When using, it is important to strictly follow the doctor's advice and not adjust the dosage or discontinue the medication on your own.
3. Patients should be closely monitored for their reactions and seek medical attention promptly when necessary.